Searchable abstracts of presentations at key conferences in obesity
Previous issue | Volume 2 | OU2020 | Next issue

Obesity Update 2020

London, UK
13 Feb 2020 - 13 Feb 2020

Card image cap
Obesity Update 2020 brings together a review of the last year, plenaries, debate and case discussions.


Case Discussions: Complex Clinical Cases 1

ob0002cd1.1 | Case Discussions: Complex Clinical Cases 1 | OU2020

The prevalence and impact of obesity in adults with type 1 diabetes; a cross-sectional study

Cantley Nathan , Lonnen Kathryn , Kahal Hassan

Background: Obesity has largely been associated with type 2 diabetes, while people with type 1 diabetes (T1DM) are usually lean at diagnosis. Given the growing prevalence of obesity in the general population, people with T1DM are at increased risk of weight gain, insulin resistance and developing ‘double diabetes (DD)’. People with DD are at increased risk of micro/macrovascular complications and mortality. In this study we aimed to examine the prevalence and impact ...

ob0002cd1.2 | Case Discussions: Complex Clinical Cases 1 | OU2020

A case of refractory euglycemic diabetic ketoacidosis post elective bariatric surgery

Khan Huma Humayun , Dubiwa Ester , Htet Zaw Ye , Aung Theingi , Kavvoura Foteini

SGLT2 inhibitors (SGLT2Is) are increasingly prescribed for patients with Type 2 Diabetes (T2D) as they are associated with cardiovascular benefit and weight loss with low risk of hypoglycaemia. However, in the last few years, euglycemic ketoacidosis has emerged as a recognized complication of treatment with SGLT2I. The challenge lies in delayed recognition and treatment as it can be easily overlooked due to the conspicuous absence of marked hyperglycaemia. Ketoacidosis can als...

ob0002cd1.3 | Case Discussions: Complex Clinical Cases 1 | OU2020

The use of Somatostatin Analogue and Novel use of Freestyle Libre™ continuous blood sugar monitoring in refractory Hyperinsulinaemic Hypoglycaemia Post Bariatric Surgery

Pillai Sanesh , Munir Alia

Bariatric surgery has increasingly been associated with complications including hyperinsulinaemic hypoglycaemia associated primarily with early and late dumping syndrome, with a suggested prevalence of 0.36% (1). The symptoms can be extremely problematic with late dumping often presenting several years after surgery (1). Here we summarise the management in two such patients. Case 1: A 44 year old lady with a history of successful Roux-en-Y gastric bypass surgery (6 years prior...

ob0002cd1.4 | Case Discussions: Complex Clinical Cases 1 | OU2020

Liraglutide downregulates the expression of miRNA-424 in patients with obesity

Dimitriadis Georgios K , Dimitri Federica , Bate Danielle , Leca Bianca , Davasgaium Allan , Tripathi Gyanendra , Miras Alexander D , Rubino Francesco , Christian Mark , Randeva Harpal S

Aims: Liraglutide 3 mg once daily is an approved, prescription injectable Glucagon Like Peptide-1 receptor agonist that, when used with a low-calorie diet and increased physical activity, can reduce excess weight in patients with obesity. MiRNAs are small non-coding single stranded RNAs that regulate gene expression post-transcriptionally by inhibiting their mRNA target translation into proteins. MiRNAs can be secreted in the blood stream and affect the molecular pathways of d...