Searchable abstracts of presentations at key conferences in obesity

ob0004p7 | Presented Posters | OU2024

Using CGM to Differentiate Hypoglycaemia as a Cause of Seizures following Bariatric Surgery: A Case Report

Xia Mona , Ansari Saleem , Tan Tricia

Background: Seizures post-bariatric surgery are rarely reported yet are clinically significant. Severe postprandial hypoglycaemia can present as seizures in a patient with a history of bariatric surgery. However, differentiating between primary seizure disorders and hypoglycaemia-causing seizures can be challenging.History: A 57-year-old female presented to our bariatric clinic with frequent seizures, occurring approxima...

ob0004oc2 | Oral Communications | OU2024

Associations between weight loss pre-hip or pre-knee arthroplasty and peri- and post-operative outcomes

Gill Moneet , Lindsay Timothy , Llanera David , Tan Tricia , Liddle Alex , Izzi-Engbeaya Chioma

Obesity is an important modifiable risk factor for developing osteoarthritis. Arthroplasty improves mobility and quality of life in those with osteoarthritis. BMI thresholds are mandated by some commissioning bodies in the UK, leading to extended waiting times for arthroplasty. Obesity is associated with increased complications after arthroplasty. It is unknown if these risks can be mitigated by weight loss pre-operatively. Our systematic review and meta-analysis explores the ...

ob0004p2 | Presented Posters | OU2024

Weight management in women with subfertility seeking assisted reproduction: a case series

Abdel-Malek Mariana , Izzi-Engbeaya Chioma , Upton Jessica , Tweedlie Lucy , Hameed Saira , Scholtz Samantha , Chahal Harvinder , Tan Tricia

The impact of obesity on fertility and pregnancy is well-established. The literature remains conflicting around optimal BMI threshold and weight loss strategy on reproductive outcomes. We describe a series of twenty-six women with obesity that were planning a future pregnancy or seeking assisted fertility services. They were initially reviewed for weight management at Imperial College Healthcare between September 2020 and September 2022. Clinical case information was retrieved...

ob0004p10 | Presented Posters | OU2024

The sight-saving role of Bariatric Surgery in Idiopathic Intracranial Hypertension

Abdel-Malek Mariana , Aggarwal Ravi , Brolly Louisa , Scholtz Samantha , Pambakian Alidz , Wilson Mark , Ahmed Ahmed , Tan Tricia

Idiopathic intracranial hypertension (IIH) classically occurs in women with obesity and is characterised by raised intracranial pressure. Weight loss leads to reduction in intracranial pressure. We present a case of a 35-year-old female who was urgently referred to Imperial Weight Centre. She had recently undergone revision of a right ventriculoperitoneal shunt for longstanding IIH which had not resolved her high-pressure symptoms and continued to require therapeutic lumbar pu...

ob0003p5 | All items | OU2021

Energy expenditure trends in patients following roux-en-y gastric bypass surgery

Tabbakh Yasmin , Alexiadou Kleopatra , Malallah Khalefah , Tsironis Christos , Hakky Sherif , Purkayastha Sanjay , Tan Tricia , Ahmed Ahmed

Background: Resting energy expenditure (REE) and diet induced thermogenesis (DIT) are known to influence long term maintenance of weight loss following bariatric surgery. Although it is known that fat free mass (FFM) contributes to REE to a greater extent than fat mass (FM), there has been relatively little work looking at the REE:FFM ratio and its overall effect on and relationship to weight loss.Aim: To assess weight loss, REE and REE:MMT ratio in pati...

ob0002p8 | (1) | OU2020

Proglucagon peptide secretion post Roux-en-Y gastric bypass: one year prospective study

Alexiadou Kleopatra , Cuenco Joyceline , Howard James , Albrechtsen Nicolai Wewer , Ilesanmi Ibeyimi , Kamocka Anna , Tharakan George , Behary Preeshila , Ahmed Ahmed R , Holst Jens J , Bloom Stephen R , Khoo Bernard , Tan Tricia M

Background: Hyperglucagonaemia is one of the key players in the pathophysiology of type 2 diabetes. Roux-en-Y Gastric Bypass (RYGB) is currently a highly effective treatment for weight loss and diabetes remission. However, the role of glucagon in the above effects is unclear.Aim: To characterise the behaviour of proglucagon-derived peptides (glucagon, glucagon-like peptide-1, oxyntomodulin, glicentin) after RYGB surgery.Subjects an...

ob0003cd2.2 | Case Discussions 2 | OU2021

Glycaemic variability assessed by continuous glucose monitoring after Roux-en-Y gastric bypass vs. sleeve gastrectomy

Alexiadou Kleopatra , Malallah Khalefah , Ilesanmi Ibiyemi , Tabbakh Yasmin , Kenkre Julia , Choudhury Sirazum , Behary Preeshila , Tharakan George , Purkayastha Sanjay , Tsironis Christos , Hakky Sherif , Ahmed Ahmed R , Bloom Stephen R , Tan Tricia M

Background: Roux-en-Y Gastric Bypass (RYGB) and Sleeve Gastrectomy are two widely used bariatric procedures. Longitudinal data have shown similar efficacy in terms of sustained weight loss and diabetes remission in obese patients with type 2 diabetes. Altered glucose dynamics with increased glycaemic variability and the occurrence of hypoglycaemia are common post-bariatric surgery. Aim: To compare the glycaemic variability and incidence of hypoglycaemia ...

ob0004p3 | Presented Posters | OU2024

Proposed prioritisation framework for the introduction of new medical therapies for weight management in the NHS

Boyle Luke D , Albor Christo , Anyiam Oluwaseun , Sen Gupta Piya , Coelho Claudia , Crane James , K Dimitriadis Georgios , Andrews Robert , Hughes David , Idris Iskandar , Tan Tricia , M McGowan Barbara , McCullough Kath

Until recently, only two medications were licenced and approved by the National Institute of Health and Care Excellence (NICE) for weight loss, orlistat and liraglutide. Semaglutide 2.4mg was launched in September 2023. Both liraglutide and semaglutide belong to a class of drugs called GLP-1 analogues, also used in the treatment of Type 2 diabetes. Successful weight loss outcomes for GLP-1 analogues has led to increased global demand and shortages. In June 2023, a National Pat...